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The Ligand Trans Influence Governs Conformation in Cobalamin-Dependent Methionine Synthase

Cobalamin-dependent methionine synthase (MetH) of Escherichia coli is a large, modular enzyme that uses a cobalamin prosthetic group as a donor or acceptor in three separate methyl transfer reactions. The prosthetic group alternates between methylcobalamin and cob(I)alamin during catalysis as homocy...

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Main Authors: Fleischhacker, Angela S., Matthews, Rowena G.
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2548328/
https://ncbi.nlm.nih.gov/pubmed/17924667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi701367c
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