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Overexpression of Spry1 in Chondrocytes Causes Attenuated FGFR Ubiquitination and Sustained ERK Activation Resulting in Chondrodysplasia

The FGF signaling pathway plays essential roles in endochondral ossification by regulating osteoblast proliferation and differentiation, chondrocyte proliferation, hypertrophy, and apoptosis. FGF signaling is controlled by the complementary action of both positive and negative regulators of the sign...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Yang, Xuehui, Harkins, Lauren K., Zubanova, Olga, Harrington, Anne, Kovalenko, Dmitry, Nadeau, Robert J., Chen, Pei-Yu, Toher, Jessica L., Lindner, Volkhard, Liaw, Lucy, Friesel, Robert
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2548288/
https://ncbi.nlm.nih.gov/pubmed/18582454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.05.555
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