Overexpression of Spry1 in Chondrocytes Causes Attenuated FGFR Ubiquitination and Sustained ERK Activation Resulting in Chondrodysplasia

The FGF signaling pathway plays essential roles in endochondral ossification by regulating osteoblast proliferation and differentiation, chondrocyte proliferation, hypertrophy, and apoptosis. FGF signaling is controlled by the complementary action of both positive and negative regulators of the sign...

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Bibliografski detalji
Glavni autori: Yang, Xuehui, Harkins, Lauren K., Zubanova, Olga, Harrington, Anne, Kovalenko, Dmitry, Nadeau, Robert J., Chen, Pei-Yu, Toher, Jessica L., Lindner, Volkhard, Liaw, Lucy, Friesel, Robert
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2548288/
https://ncbi.nlm.nih.gov/pubmed/18582454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.05.555
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