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Overexpression of Spry1 in Chondrocytes Causes Attenuated FGFR Ubiquitination and Sustained ERK Activation Resulting in Chondrodysplasia

The FGF signaling pathway plays essential roles in endochondral ossification by regulating osteoblast proliferation and differentiation, chondrocyte proliferation, hypertrophy, and apoptosis. FGF signaling is controlled by the complementary action of both positive and negative regulators of the sign...

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محفوظ في:

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Yang, Xuehui, Harkins, Lauren K., Zubanova, Olga, Harrington, Anne, Kovalenko, Dmitry, Nadeau, Robert J., Chen, Pei-Yu, Toher, Jessica L., Lindner, Volkhard, Liaw, Lucy, Friesel, Robert
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	2008
الموضوعات:	Article
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2548288/ https://ncbi.nlm.nih.gov/pubmed/18582454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.05.555
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Overexpression of Spry1 in Chondrocytes Causes Attenuated FGFR Ubiquitination and Sustained ERK Activation Resulting in Chondrodysplasia

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