Focal Adhesion Targeting: The Critical Determinant of FAK Regulation and Substrate Phosphorylation
The focal adhesion kinase (FAK) is discretely localized to focal adhesions via its C-terminal focal adhesion–targeting (FAT) sequence. FAK is regulated by integrin-dependent cell adhesion and can regulate tyrosine phosphorylation of downstream substrates, like paxillin. By the use of a mutational st...
Gardado en:
| Publicado en: | Mol Biol Cell |
|---|---|
| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Cell Biology
1999
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25482/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10436008/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.10.8.2507 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|