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Modeling Subunit Cooperativity in Opening of Tetrameric Ion Channels

Most potassium channels are tetramers of four homologous polypeptides (subunits). During channel gating, each subunit undergoes several conformational changes independent of the state of other subunits before reaching a permissive state, from which the channel can open. However, transition from the...

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Bibliografski detalji
Glavni autori: Nekouzadeh, Ali, Silva, Jonathan R., Rudy, Yoram
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547442/
https://ncbi.nlm.nih.gov/pubmed/18621838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.136721
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