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Modeling Subunit Cooperativity in Opening of Tetrameric Ion Channels
Most potassium channels are tetramers of four homologous polypeptides (subunits). During channel gating, each subunit undergoes several conformational changes independent of the state of other subunits before reaching a permissive state, from which the channel can open. However, transition from the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2547442/ https://ncbi.nlm.nih.gov/pubmed/18621838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.136721 |
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