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Insulin Fibril Nucleation: The Role of Prefibrillar Aggregates

Dynamic light scattering and Fourier transform infrared spectroscopy were used to study the formation of prefibrillar aggregates and fibrils of bovine pancreatic insulin at 60°C and at pH 1. The kinetics of disintegration of the prefibrillar aggregates were also studied using these techniques after...

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Detalhes bibliográficos
Main Authors: Smith, M. I., Sharp, J. S., Roberts, C. J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547439/
https://ncbi.nlm.nih.gov/pubmed/18599629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.131482
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