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Mechanisms of Protein Fibril Formation: Nucleated Polymerization with Competing Off-Pathway Aggregation
The formation of protein fibrils, and in particular amyloid fibrils, underlies many human diseases. Understanding fibril formation mechanisms is important for understanding disease pathology, but fibril formation kinetics can be complicated, making the relationship between experimental observables a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2157252/ https://ncbi.nlm.nih.gov/pubmed/17890392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.117168 |
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