The Structure of the Amyloid-β Peptide High-Affinity Copper II Binding Site in Alzheimer Disease

Neurodegeneration observed in Alzheimer disease (AD) is believed to be related to the toxicity from reactive oxygen species (ROS) produced in the brain by the amyloid-β (Aβ) protein bound primarily to copper ions. The evidence for an oxidative stress role of Aβ-Cu redox chemistry is still incomplete...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Streltsov, Victor A., Titmuss, Stephen J., Epa, V. Chandana, Barnham, Kevin J., Masters, Colin L., Varghese, Joseph N.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Spectroscopy, Imaging, Other Techniques
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547438/
https://ncbi.nlm.nih.gov/pubmed/18599641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.134429
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados