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Widespread hyperplasia induced by transgenic TGFα in Apc(Min) mice is associated with only regional effects on tumorigenesis

Using a mouse predisposed to neoplasia by a germ line mutation in Apc (Apc(Min)), we tested whether induced hyperplasia is sufficient to increase intestinal tumor multiplicity or size in the intestine. We found that hyperplasia in the jejunum correlated with a significant increase in tumor multiplic...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Bilger, Andrea, Sullivan, Ruth, Prunuske, Amy J., Clipson, Linda, Drinkwater, Norman R., Dove, William F.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547353/
https://ncbi.nlm.nih.gov/pubmed/18310091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn038
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