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Widespread hyperplasia induced by transgenic TGFα in Apc(Min) mice is associated with only regional effects on tumorigenesis
Using a mouse predisposed to neoplasia by a germ line mutation in Apc (Apc(Min)), we tested whether induced hyperplasia is sufficient to increase intestinal tumor multiplicity or size in the intestine. We found that hyperplasia in the jejunum correlated with a significant increase in tumor multiplic...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2008
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2547353/ https://ncbi.nlm.nih.gov/pubmed/18310091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn038 |
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