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Dynamics of Nucleotide Incorporation: Snapshots Revealed by 2-Aminopurine Fluorescence Studies
Formation of a noncanonical base pair between dFTP, a dTTP analogue that cannot form H bonds, and the fluorescent base analogue 2-aminopurine (2AP) was studied in order to discover how the bacteriophage T4 DNA polymerase selects nucleotides with high accuracy. Changes in 2AP fluorescence intensity p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2547141/ https://ncbi.nlm.nih.gov/pubmed/16503638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi051644s |
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