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Dynamics of the IRE RNA hairpin loop probed by 2-aminopurine fluorescence and stochastic dynamics simulations

The iron responsive element (IRE) RNA hairpin loop contains six phylogenetically conserved nucleotides, which constitute part of the sequence-specific binding site of the IRE-binding protein. The NMR structure of the loop has been solved, showing that 3 of the 6 nt are poorly constrained. Here, two...

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Detalhes bibliográficos
Main Authors: HALL, KATHLEEN B., WILLIAMS, D. JEREMY
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 by RNA Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370516/
https://ncbi.nlm.nih.gov/pubmed/14681583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5133404
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