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Crystal Structure of Human Edc3 and Its Functional Implications

Edc3 is an enhancer of decapping and serves as a scaffold that aggregates mRNA ribonucleoproteins together for P-body formation. Edc3 forms a network of interactions with the components of the mRNA decapping machinery and has a modular domain architecture consisting of an N-terminal Lsm domain, a ce...

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Autori principali: Ling, Sharon H. M., Decker, Carolyn J., Walsh, Martin A., She, Meipei, Parker, Roy, Song, Haiwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2547010/
https://ncbi.nlm.nih.gov/pubmed/18678652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00761-08
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