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Recombination between a defective retrovirus and homologous sequences in host DNA: reversion by patch repair.

The genomes of mammalian species contain multiple copies of sequences homologous to exogenous retroviruses. When a mutant retrovirus carrying a lethal deletion in an essential viral gene was introduced into mammalian cells, revertant viruses appeared and spread throughout the culture. Analysis of on...

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Библиографические подробности
Главные авторы: Schwartzberg, P, Colicelli, J, Goff, S P
Формат: Artigo
Язык:Inglês
Опубликовано: 1985
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC254699/
https://ncbi.nlm.nih.gov/pubmed/2983084
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