Dynamic Histone H3 Acetylation and Methylation at Human Cytomegalovirus Promoters during Replication in Fibroblasts

Human cytomegalovirus DNA is packaged in virions without histones but associates with histones upon reaching the nucleus of an infected cell. Since transcription is modulated by the interplay of histone modifications, we used chromatin immunoprecipitation to detect acetylation and methylation of his...

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Bibliographic Details
Main Authors: Cuevas-Bennett, Christian, Shenk, Thomas
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546956/
https://ncbi.nlm.nih.gov/pubmed/18653451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00946-08
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