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Human Cytomegalovirus Gene UL21a Encodes a Short-Lived Cytoplasmic Protein and Facilitates Virus Replication in Fibroblasts

The human cytomegalovirus (HCMV) gene UL21a was recently annotated by its conservation in chimpanzee cytomegalovirus. Two large-scale mutagenic analyses showed that mutations in overlapping UL21a/UL21 resulted in a severe defect of virus growth in fibroblasts. Here, we characterized UL21a and demons...

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Detalhes bibliográficos
Main Authors: Fehr, Anthony R., Yu, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798419/
https://ncbi.nlm.nih.gov/pubmed/19846516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01116-09
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