ERK1/2-Mediated Phosphorylation of Small Hepatitis Delta Antigen at Serine 177 Enhances Hepatitis Delta Virus Antigenomic RNA Replication

The small hepatitis delta virus (HDV) antigen (SHDAg) plays an essential role in HDV RNA double-rolling-circle replication. Several posttranslational modifications (PTMs) of HDAgs, including phosphorylation, acetylation, and methylation, have been characterized. Among the PTMs, the serine 177 residu...

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Bibliographic Details
Main Authors: Chen, Yen-Shun, Huang, Wen-Hung, Hong, Shiao-Ya, Tsay, Yeou-Guang, Chen, Pei-Jer
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546944/
https://ncbi.nlm.nih.gov/pubmed/18632853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00656-08
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