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Nucleolar Targeting of Hepatitis Delta Antigen Abolishes Its Ability To Initiate Viral Antigenomic RNA Replication

Hepatitis delta virus (HDV) is a small RNA virus that contains one 1.7-kb single-stranded circular RNA of negative polarity. The HDV particle also contains two isoforms of hepatitis delta antigen (HDAg), small (SHDAg) and large HDAg. SHDAg is required for the replication of HDV, which is presumably...

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Autors principals: Huang, Wen-Hung, Chen, Yen-Shun, Chen, Pei-Jer
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224599/
https://ncbi.nlm.nih.gov/pubmed/17989182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01155-07
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