Nucleolar Targeting of Hepatitis Delta Antigen Abolishes Its Ability To Initiate Viral Antigenomic RNA Replication

Hepatitis delta virus (HDV) is a small RNA virus that contains one 1.7-kb single-stranded circular RNA of negative polarity. The HDV particle also contains two isoforms of hepatitis delta antigen (HDAg), small (SHDAg) and large HDAg. SHDAg is required for the replication of HDV, which is presumably...

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Hlavní autoři: Huang, Wen-Hung, Chen, Yen-Shun, Chen, Pei-Jer
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224599/
https://ncbi.nlm.nih.gov/pubmed/17989182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01155-07
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