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Nucleolar Targeting of Hepatitis Delta Antigen Abolishes Its Ability To Initiate Viral Antigenomic RNA Replication

Hepatitis delta virus (HDV) is a small RNA virus that contains one 1.7-kb single-stranded circular RNA of negative polarity. The HDV particle also contains two isoforms of hepatitis delta antigen (HDAg), small (SHDAg) and large HDAg. SHDAg is required for the replication of HDV, which is presumably...

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Detalles Bibliográficos
Main Authors: Huang, Wen-Hung, Chen, Yen-Shun, Chen, Pei-Jer
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224599/
https://ncbi.nlm.nih.gov/pubmed/17989182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01155-07
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