ERK1/2-Mediated Phosphorylation of Small Hepatitis Delta Antigen at Serine 177 Enhances Hepatitis Delta Virus Antigenomic RNA Replication

The small hepatitis delta virus (HDV) antigen (SHDAg) plays an essential role in HDV RNA double-rolling-circle replication. Several posttranslational modifications (PTMs) of HDAgs, including phosphorylation, acetylation, and methylation, have been characterized. Among the PTMs, the serine 177 residu...

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Main Authors: Chen, Yen-Shun, Huang, Wen-Hung, Hong, Shiao-Ya, Tsay, Yeou-Guang, Chen, Pei-Jer
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546944/
https://ncbi.nlm.nih.gov/pubmed/18632853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00656-08
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