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Human Immunodeficiency Virus Type 1 Vif Induces Cell Cycle Delay via Recruitment of the Same E3 Ubiquitin Ligase Complex That Targets APOBEC3 Proteins for Degradation

Human immunodeficiency virus type 1 (HIV-1) Vif recruits a Cullin 5 ubiquitin ligase that targets APOBEC3 proteins for degradation. Recently, Vif has also been shown to induce cell cycle disturbance in G(2). We show that in contrast to the expression of Vpr, the expression of Vif does not preclude c...

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Detalles Bibliográficos
Main Authors: DeHart, Jason L., Bosque, Alberto, Harris, Reuben S., Planelles, Vicente
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546900/
https://ncbi.nlm.nih.gov/pubmed/18596088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00377-08
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