Distinct Requirements of Adenovirus E1b55K Protein for Degradation of Cellular Substrates

The E1b55K and E4orf6 proteins of adenovirus type 5 (Ad5) assemble into a complex together with cellular proteins including cullin 5, elongins B and C, and Rbx1. This complex possesses E3 ubiquitin ligase activity and targets cellular proteins for proteasome-mediated degradation. The ligase activity...

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Detaylı Bibliyografya
Asıl Yazarlar: Schwartz, Rachel A., Lakdawala, Seema S., Eshleman, Heather D., Russell, Matthew R., Carson, Christian T., Weitzman, Matthew D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Cellular Response to Infection
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546875/
https://ncbi.nlm.nih.gov/pubmed/18614635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00925-08
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