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Distinct Requirements of Adenovirus E1b55K Protein for Degradation of Cellular Substrates
The E1b55K and E4orf6 proteins of adenovirus type 5 (Ad5) assemble into a complex together with cellular proteins including cullin 5, elongins B and C, and Rbx1. This complex possesses E3 ubiquitin ligase activity and targets cellular proteins for proteasome-mediated degradation. The ligase activity...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2546875/ https://ncbi.nlm.nih.gov/pubmed/18614635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00925-08 |
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