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Characterization of an Inducible, Antibiotic-Resistant Aminoacyl-tRNA Synthetase Gene in Streptomyces coelicolor

Streptomyces coelicolor has two genes encoding tryptophanyl-tRNA synthetases, one of which (trpRS1) is resistant to and transcriptionally activated by indolmycin. We found that this gene also confers resistance to chuangxinmycin (another antibiotic that inhibits bacterial tryptophanyl-tRNA synthetas...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vecchione, James J., Sello, Jason K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546804/
https://ncbi.nlm.nih.gov/pubmed/18621902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00737-08
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