Noncoding RNA of Glutamine Synthetase I Modulates Antibiotic Production in Streptomyces coelicolor A3(2)

Overexpression of antisense chromosomal cis-encoded noncoding RNAss (ncRNAs) in glutamine synthetase I resulted in a decrease in growth, protein synthesis, and antibiotic production in Streptomyces coelicolor. In addition, we predicted 3,597 cis-encoded ncRNAs and validated 13 of them experimentally...

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Bibliografske podrobnosti
Main Authors: D'Alia, Davide, Nieselt, Kay, Steigele, Stephan, Müller, Jonas, Verburg, Ilse, Takano, Eriko
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Genetics and Molecular Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812974/
https://ncbi.nlm.nih.gov/pubmed/19966003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01374-09
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