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The efficient syntheses of 5′-deoxy-5′-fluoro -guanosine and –inosine
[Image: see text] Substitution of oxygen with a weak hydrogen bond acceptor such as fluorine provides a single-atom modification that can have grave effects on the chemical and medicinal properties of nucleoside analogs. To that end, we present a simple and high yielding method for the novel synthes...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2546599/ https://ncbi.nlm.nih.gov/pubmed/17902696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo7015778 |
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