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Enantioselective Total Synthesis of FD-891

[Image: see text] The enantioselective synthesis of FD-891 has been achieved with a longest linear sequence of 21 steps. The synthetic strategy involves the use of aldol additions of a chlorotitanium enolate of N-acylthiazolidinthiones as the key reaction to establish 6 of the 10 stereogenic centers...

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Autores principales: Crimmins, Michael T., Caussanel, Franck
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546579/
https://ncbi.nlm.nih.gov/pubmed/16522077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja060018v
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