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Enantioselective Total Synthesis of Brevetoxin A: Convergent Coupling Strategy and Completion

A highly convergent, enantioselective total synthesis of brevetoxin A is reported. The development of a [X + 2 + X] Horner–Wadsworth–Emmons/cyclodehydration/reductive etherification convergent coupling strategy allowed for a unified approach to the synthesis of two advanced tetracyclic fragments fro...

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Detalhes bibliográficos
Main Authors: Crimmins, Michael T., Zuccarello, J. Lucas, McDougall, Patrick J., Ellis, J. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826122/
https://ncbi.nlm.nih.gov/pubmed/19655349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.200900777
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