Chemoprevention of 7, 12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch by topical application of a dual inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 tyrosine kinases

Oral cancer is a common neoplasm worldwide with tobacco and alcohol being the major etiological factors contributing to its pathogenesis. Epidermal growth factor receptor (EGFR) and ErbB2 are known to be involved in the development of oral cancer with the former up-regulated in up to 90% human cases...

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Detalhes bibliográficos
Main Authors: Sun, Zheng, Sood, Sandeep, Li, Ning, Yang, Peiying, Newman, Robert A., Yang, Chung S., Chen, Xiaoxin
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546572/
https://ncbi.nlm.nih.gov/pubmed/17936675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2007.08.006
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