Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced Hamster Cheek Pouch Carcinogenesis by a 5-Lipoxygenase Inhibitor, Garcinol

Our previous studies have shown that aberrant arachidonic acid metabolism, especially the 5-lipoxygenase (5-Lox) pathway, is involved in oral carcinogenesis, and can be targeted for cancer prevention. In order to develop potent topical agents for oral cancer chemoprevention, five known 5-Lox inhibit...

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Detalhes bibliográficos
Main Authors: Chen, Xin, Zhang, Xinyan, Lu, Ye, Shim, Joong-Youn, Sang, Shengmin, Sun, Zheng, Chen, Xiaoxin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780792/
https://ncbi.nlm.nih.gov/pubmed/23137051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01635581.2012.718032
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