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High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma
The childhood cancer neuroblastoma arises in the developing sympathetic nervous system and is a genotypically and phenotypically heterogeneous disease. Prognostic markers of poor survival probability include amplification of the MYCN oncogene and an undifferentiated morphology. Whereas these feature...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2544584/ https://ncbi.nlm.nih.gov/pubmed/18780787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804455105 |
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