Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload

Pim-1 kinase exerts potent cardioprotective effects in the myocardium downstream of AKT, but the participation of Pim-1 in cardiac hypertrophy requires investigation. Cardiac-specific expression of Pim-1 (Pim-WT) or the dominant-negative mutant of Pim-1 (Pim-DN) in transgenic mice together with aden...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Muraski, John A., Fischer, Kimberlee M., Wu, Weitao, Cottage, Christopher T., Quijada, Pearl, Mason, Matt, Din, Shabana, Gude, Natalie, Alvarez, Roberto, Rota, Marcello, Kajstura, Jan, Wang, Zeping, Schaefer, Erik, Chen, Xiongen, MacDonnel, Scott, Magnuson, Nancy, Houser, Stephen R., Anversa, Piero, Sussman, Mark A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544549/
https://ncbi.nlm.nih.gov/pubmed/18784362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709135105
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares