Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload

Pim-1 kinase exerts potent cardioprotective effects in the myocardium downstream of AKT, but the participation of Pim-1 in cardiac hypertrophy requires investigation. Cardiac-specific expression of Pim-1 (Pim-WT) or the dominant-negative mutant of Pim-1 (Pim-DN) in transgenic mice together with aden...

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Detaylı Bibliyografya
Asıl Yazarlar: Muraski, John A., Fischer, Kimberlee M., Wu, Weitao, Cottage, Christopher T., Quijada, Pearl, Mason, Matt, Din, Shabana, Gude, Natalie, Alvarez, Roberto, Rota, Marcello, Kajstura, Jan, Wang, Zeping, Schaefer, Erik, Chen, Xiongen, MacDonnel, Scott, Magnuson, Nancy, Houser, Stephen R., Anversa, Piero, Sussman, Mark A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544549/
https://ncbi.nlm.nih.gov/pubmed/18784362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709135105
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