Conditioning the heart induces formation of signalosomes that interact with mitochondria to open mitoK(ATP) channels

Perfusion of the heart with bradykinin triggers cellular signaling events that ultimately cause opening of mitochondrial ATP-sensitive K(+) (mitoK(ATP)) channels, increased H(2)O(2) production, inhibition of the mitochondrial permeability transition (MPT), and cardioprotection. We hypothesized that...

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Detalhes bibliográficos
Main Authors: Quinlan, Casey L., Costa, Alexandre D. T., Costa, Cinthia L., Pierre, Sandrine V., Dos Santos, Pierre, Garlid, Keith D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544503/
https://ncbi.nlm.nih.gov/pubmed/18621853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00520.2008
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