Conditioning the heart induces formation of signalosomes that interact with mitochondria to open mitoK(ATP) channels

Perfusion of the heart with bradykinin triggers cellular signaling events that ultimately cause opening of mitochondrial ATP-sensitive K(+) (mitoK(ATP)) channels, increased H(2)O(2) production, inhibition of the mitochondrial permeability transition (MPT), and cardioprotection. We hypothesized that...

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Autori principali: Quinlan, Casey L., Costa, Alexandre D. T., Costa, Cinthia L., Pierre, Sandrine V., Dos Santos, Pierre, Garlid, Keith D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2544503/
https://ncbi.nlm.nih.gov/pubmed/18621853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00520.2008
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