Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs

Tregs are important mediators of immune tolerance to self antigens, and it has been suggested that Treg inactivation may cause autoimmune disease. Therefore, immunotherapy approaches that aim to restore or expand autoantigen-specific Treg activity might be beneficial for the treatment of autoimmune...

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Main Authors: Lüth, Stefan, Huber, Samuel, Schramm, Christoph, Buch, Thorsten, Zander, Stefan, Stadelmann, Christine, Brück, Wolfgang, Wraith, David C., Herkel, Johannes, Lohse, Ansgar W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542846/
https://ncbi.nlm.nih.gov/pubmed/18802476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32132
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