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The C-terminal Domain of p21 Inhibits Nucleotide Excision Repair In Vitro and In Vivo

The protein p21(Cip1, Waf1, Sdi1) is a potent inhibitor of cyclin-dependent kinases (CDKs). p21 can also block DNA replication through its interaction with the proliferating cell nuclear antigen (PCNA), which is an auxiliary factor for polymerase δ. PCNA is also implicated in the repair resynthesis...

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Bibliografiska uppgifter
Huvudupphovsmän: Cooper, Marcus P., Balajee, Adayabalam S., Bohr, Vilhelm A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 1999
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC25424/
https://ncbi.nlm.nih.gov/pubmed/10397753
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