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Differential requirement for the ATPase domain of the Cockayne syndrome group B gene in the processing of UV-induced DNA damage and 8-oxoguanine lesions in human cells

Cockayne syndrome (CS) is a rare inherited human genetic disorder characterized by UV sensitivity, developmental abnormalities and premature aging. The cellular and molecular phenotypes of CS include increased sensitivity to oxidative and UV-induced DNA lesions. The CSB protein is thought to play a...

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Detalhes bibliográficos
Main Authors: Selzer, Rebecca R., Nyaga, Simon, Tuo, Jingsheng, May, Alfred, Muftuoglu, Meltem, Christiansen, Mette, Citterio, Elisabetta, Brosh, Robert M., Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC100288/
https://ncbi.nlm.nih.gov/pubmed/11809892
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