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A matter of delicate balance: Loss and gain of Cockayne syndrome proteins in premature aging and cancer

DNA repair genes are critical for preserving genomic stability and it is well established that mutations in DNA repair genes give rise to progeroid diseases due to perturbations in different DNA metabolic activities. Cockayne Syndrome (CS) is an autosomal recessive inheritance caused by inactivating...

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Bibliografische Detailangaben
Hauptverfasser: Elena Paccosi, Adayabalam S. Balajee, Luca Proietti-De-Santis
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2022-07-01
Schriftenreihe:Frontiers in Aging
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fragi.2022.960662/full
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