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Genetic regulation of MUC1 alternative splicing in human tissues

The membrane mucin MUC1 is aberrantly expressed in a variety of cancers, and in stomach, it is a ligand for Helicobacter pylori where it plays a role in gastric carcinogenesis. Splicing variation, leading to a 9-amino acid insertion in the signal peptide region, was proposed to be because of a singl...

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Bibliografiske detaljer
Main Authors: Ng, W, Loh, A X W, Teixeira, A S, Pereira, S P, Swallow, D M
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538764/
https://ncbi.nlm.nih.gov/pubmed/19238635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604617
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