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Structural Determinants of Opioid Activity in Derivatives of 14-Aminomorphinones: Effects of Changes to the Chain Linking the C(14)-Amino Group to the Aryl Ring

The 14-aminodihydromorphinone and codeinone series of opioid ligands have produced a number of ligands of substantial interest. In order to investigate the importance of the 14-substituent a series of analogues in which the side chain length is varied and the amide and alkene functions are reduced h...

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Detaylı Bibliyografya
Asıl Yazarlar: Rennison, David, Moynihan, Humphrey, Traynor, John R., Lewis, John W., Husbands., Stephen M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538686/
https://ncbi.nlm.nih.gov/pubmed/17004724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm060595u
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