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Structural Determinants of Opioid Activity in Derivatives of 14-Aminomorphinones: Effects of Changes to the Chain Linking the C(14)-Amino Group to the Aryl Ring
The 14-aminodihydromorphinone and codeinone series of opioid ligands have produced a number of ligands of substantial interest. In order to investigate the importance of the 14-substituent a series of analogues in which the side chain length is varied and the amide and alkene functions are reduced h...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538686/ https://ncbi.nlm.nih.gov/pubmed/17004724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm060595u |
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