Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve

Peripheral sensory neurons respond to axon injury by activating an importin-dependent retrograde signaling mechanism. How is this mechanism regulated? Here we show that Ran GTPase and its associated effectors RanBP1 and RanGAP regulate the formation of importin signaling complexes in injured axons....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yudin, Dmitry, Hanz, Shlomit, Yoo, Soonmoon, Iavnilovitch, Elena, Willis, Dianna, Gradus, Tal, Vuppalanchi, Deepika, Segal-Ruder, Yael, Ben-Yaakov, Keren, Hieda, Miki, Yoneda, Yoshihiro, Twiss, Jeffery L., Fainzilber, Mike
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538677/
https://ncbi.nlm.nih.gov/pubmed/18667152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.05.029
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