R57K Polymorphism in the Human Immunodeficiency Virus Type 1 Protease as Predictor of Early Virological Failure in a Cohort of Antiretroviral-Naive Patients Treated Mostly with a Nelfinavir-Containing Regimen

In 243 antiretroviral-naive human immunodeficiency-infected patients starting a first-line-protease inhibitor (mainly nelfinavir)-containing therapy, the presence of the polymorphism R57K in the protease at the inception of therapy was independently associated with a higher rate of virological failu...

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Detalhes bibliográficos
Main Authors: Masquelier, Bernard, Droz, Cecile, Dary, Martin, Perronne, Christian, Ferré, Virginie, Spire, Bruno, Descamps, Diane, Raffi, François, Brun-Vézinet, Françoise, Chêne, Geneviève
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC253793/
https://ncbi.nlm.nih.gov/pubmed/14576131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.11.3623-3626.2003
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