Gag Mutations Can Impact Virological Response to Dual-Boosted Protease Inhibitor Combinations in Antiretroviral-Naïve HIV-Infected Patients

ANRS 127 was a randomized pilot trial involving naïve patients receiving two dual-boosted protease inhibitor (PI) combinations. Virological response, defined as a plasma HIV RNA level of <50 copies/ml at week 16, occurred in only 41% patients. Low baseline plasma HIV RNA level was the only signif...

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Detalhes bibliográficos
Main Authors: Larrouy, Lucile, Chazallon, C., Landman, R., Capitant, C., Peytavin, G., Collin, G., Charpentier, C., Storto, A., Pialoux, G., Katlama, C., Girard, P. M., Yeni, P., Aboulker, J. P., Brun-Vezinet, F., Descamps, D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897283/
https://ncbi.nlm.nih.gov/pubmed/20439606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00194-10
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