Positive Impact of HIV-1 gag Cleavage Site Mutations on the Virological Response to Darunavir Boosted with Ritonavir

We assessed the roles of baseline gag and gag-pol cleavage site mutations (CSM) on the virological outcome of a darunavir-based regimen in highly antiretroviral-experienced patients. We showed the association, in multivariate analysis, between the A431V gag CSM and the virological response, defined...

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Detalles Bibliográficos
Main Authors: Larrouy, Lucile, Lambert-Niclot, Sidonie, Charpentier, Charlotte, Fourati, Slim, Visseaux, Benoit, Soulié, Cathia, Wirden, Marc, Katlama, Christine, Yeni, Patrick, Brun-Vézinet, Françoise, Calvez, Vincent, Marcelin, Anne-Geneviève, Descamps, Diane
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2011
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067137/
https://ncbi.nlm.nih.gov/pubmed/21282435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01049-10
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