Simulation of Human Gentamicin Pharmacokinetics in an Experimental Enterococcus faecalis Endocarditis Model

Significant differences between animal and human pharmacokinetics may be responsible for the conflicting results of experimental studies. This study determined the impact of human pharmacokinetic simulation (HPS) on gentamicin activity in an Enterococcus faecalis endocarditis model. The decrease in...

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Bibliographic Details
Main Authors: Dubé, Laurent, Caillon, Jocelyne, Gras-Le Guen, Christèle, Jacqueline, Cédric, Kergueris, Marie-France, Granry, Jean-Claude, Potel, Gilles, Bugnon, Denis
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC253777/
https://ncbi.nlm.nih.gov/pubmed/14576143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.11.3663-3666.2003
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