Simulation of Human Gentamicin Pharmacokinetics in an Experimental Enterococcus faecalis Endocarditis Model

Significant differences between animal and human pharmacokinetics may be responsible for the conflicting results of experimental studies. This study determined the impact of human pharmacokinetic simulation (HPS) on gentamicin activity in an Enterococcus faecalis endocarditis model. The decrease in...

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Главные авторы: Dubé, Laurent, Caillon, Jocelyne, Gras-Le Guen, Christèle, Jacqueline, Cédric, Kergueris, Marie-France, Granry, Jean-Claude, Potel, Gilles, Bugnon, Denis
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2003
Предметы:
Experimental Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC253777/
https://ncbi.nlm.nih.gov/pubmed/14576143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.11.3663-3666.2003
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