Simulation of Human Gentamicin Pharmacokinetics in an Experimental Enterococcus faecalis Endocarditis Model

Significant differences between animal and human pharmacokinetics may be responsible for the conflicting results of experimental studies. This study determined the impact of human pharmacokinetic simulation (HPS) on gentamicin activity in an Enterococcus faecalis endocarditis model. The decrease in...

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Dubé, Laurent, Caillon, Jocelyne, Gras-Le Guen, Christèle, Jacqueline, Cédric, Kergueris, Marie-France, Granry, Jean-Claude, Potel, Gilles, Bugnon, Denis
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2003
Teme:
Experimental Therapeutics
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253777/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576143/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.11.3663-3666.2003
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