Simulation of Human Gentamicin Pharmacokinetics in an Experimental Enterococcus faecalis Endocarditis Model

Significant differences between animal and human pharmacokinetics may be responsible for the conflicting results of experimental studies. This study determined the impact of human pharmacokinetic simulation (HPS) on gentamicin activity in an Enterococcus faecalis endocarditis model. The decrease in...

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Autors principals: Dubé, Laurent, Caillon, Jocelyne, Gras-Le Guen, Christèle, Jacqueline, Cédric, Kergueris, Marie-France, Granry, Jean-Claude, Potel, Gilles, Bugnon, Denis
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC253777/
https://ncbi.nlm.nih.gov/pubmed/14576143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.11.3663-3666.2003
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