Simulation of Human Gentamicin Pharmacokinetics in an Experimental Enterococcus faecalis Endocarditis Model

Significant differences between animal and human pharmacokinetics may be responsible for the conflicting results of experimental studies. This study determined the impact of human pharmacokinetic simulation (HPS) on gentamicin activity in an Enterococcus faecalis endocarditis model. The decrease in...

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Bibliografische gegevens
Hoofdauteurs: Dubé, Laurent, Caillon, Jocelyne, Gras-Le Guen, Christèle, Jacqueline, Cédric, Kergueris, Marie-France, Granry, Jean-Claude, Potel, Gilles, Bugnon, Denis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2003
Onderwerpen:
Experimental Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC253777/
https://ncbi.nlm.nih.gov/pubmed/14576143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.11.3663-3666.2003
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